Tobacco Science & Technology
Tobacco Chemistry:2018 ,8:47-52
SI Xiaoxi, TANG Jianguo, ZHU Ruizhi, HAN Jingmei, YOU Junheng, LI Zhenjie, JIANG Wei, SU Zhongbi, MIAO Mingming, LIU Zhihua. Aerosol particle size distribution from an electrical heat-not-burn product under ISO and HCI smoking regimes[J]. Tobacco Science & Technology, 2018 (8): 47-52

Aerosol particle size distribution from an electrical heat-not-burn product under ISO and HCI smoking regimes
SI Xiaoxi, TANG Jianguo, ZHU Ruizhi, HAN Jingmei, YOU Junheng, LI Zhenjie, JIANG Wei, SU Zhongbi, MIAO Mingming, LIU Zhihua
Key Laboratory of Tobacco Chemistry of Yunnan, Technology Center of China Tobacco Yunnan Industrial Co., Ltd., Kunming 650231, China
Abstract:
To study the particle size distribution from commercial electric heat-not-burn products, aerosol sample was produced under the Health Canada intensive (HCI) and ISO smoking regimes by a DMS500 fast particulate spectrometer combined with a smoking cycle simulator. The results showed that:1) When the dilution ratio of the aerosol was set as 350:1, the repeatability of the results was better. 2) Under ISO and HCI smoking regimes, the particle size distribution of the aerosol from all the puffs were observed to exhibit an approximate lognormal distribution, ranging from approximately 20 to 200 nm. Under the two puffing regimes, the particle number concentration of the aerosol gradually increased and then became stable with the proceeding puffing. However, the particle number concentration under HCI regime was significantly higher than that under the ISO regime. Under the two regimes, count median diameter (CMD) of the aerosol slightly increased and then became stable, the average CMD for all the puffs was 50.2 and 58.5 nm under the HCI and ISO puffing regimes, respectively. 3) Under the ISO regime, aerosols produced from iQOSTM or gloTM heat-not-burn product were different. Particle number concentration from iQOS was significantly higher than that of glo, particle size distribution range from iQOS was narrower than from glo, while CMD of aerosol from iQOS and glo was similar. Under the ISO regime, CMD of aerosol from the heat-not-burn products was slightly bigger than that from an electronic cigarette, while significantly smaller than that from a traditional cigarette. Moreover, the puff-by-puff variations of CMD and particle number concentrations of heat-not-burn products were different from those of traditional cigarettes and electronic cigarettes.
Key words:    Cigarette    Heat-not-burn product    Electric heating    Smoke aerosol    Particle size distribution    Smoking regime   
Received: 2017-12-01     Revised: 2018-04-10
DOI: 10.16135/j.issn1002-0861.2017.0501
Corresponding author:     Email:liuzh@ynzy-tobacco.com
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Authors
SI Xiaoxi
TANG Jianguo
ZHU Ruizhi
HAN Jingmei
YOU Junheng
LI Zhenjie
JIANG Wei
SU Zhongbi
MIAO Mingming
LIU Zhihua

References:
[1] 刘珊,崔凯,曾世通,等. 加热非燃烧型烟草制品剖析[J]. 烟草科技,2016,49(11):56-65. LIU Shan,CUI Kai,ZENG Shitong,et al. Analysis of blend and aerosol composition of two heat-not-burn tobacco products[J]. Tobacco Science & Technology,2016,49(11):56-65.
[2] 李翔,谢复炜,刘惠民. 新型烟草制品毒理学评价研究进展[J]. 烟草科技,2016,49(1):88-93. LI Xiang,XIE Fuwei,LIU Huimin. Recent advances in toxicological evaluation of novel tobacco products[J]. Tobacco Science & Technology,2016,49(1):88-93.
[3] Titz B,Boué S,Phillips B,et al. Effects of cigarette smoke,cessation,and switching to two heat-not-burn tobacco products on lung lipid metabolism in C57BL/6 and Apoe-/-mice-An integrative systems toxicology analysis[J]. Toxicological Sciences,2015,149(2):441-457.
[4] 杨继,杨帅,段沅杏,等. 加热不燃烧卷烟烟草材料的热分析研究[J]. 中国烟草学报,2015,21(6):7-13. YANG Ji,YANG Shuai,DUAN Yuanxing,et al. Investigation of thermogravimetry and pyrolysis behavior of tobacco material in two heat-not-burn cigarette brands[J]. Acta Tabacaria Sinica,2015,21(6):7-13.
[5] 戴路,史春云,卢昕博,等. 加热不燃烧制品与传统卷烟再造烟叶物理特性及化学成分差异分析[J]. 中国烟草学报,2017,23(1):20-26. DAI Lu,SHI Chunyun,LU Xinbo,et al. Difference analysis on physical characteristics and chemical components of reconstituted tobacco used in traditional cigarettes and heat-not-burn tobacco products[J]. Acta Tabacaria Sinica,2017,23(1):20-26.
[6] Robinson R J,Oldham M J,Clinkenbeard R E,et al. Experimental and numerical smoke carcinogen deposition in a multi-generation human replica tracheobronchial model[J]. Annals of Biomedical Engineering,2006,34(3):373-383.
[7] Lunell E,Molander L,Ekberg K,et al. Site of nicotine absorption from a vapour inhaler-comparison with cigarette smoking[J]. European Journal of Clinical Pharmacology,2000,55(10):737-741.
[8] 吴君章,沈光林,孔浩辉,等. 卷烟烟气气溶胶粒度的研究进展[J]. 中国烟草学报,2014,20(2):108-113. WU Junzhang,SHEN Guanglin,KONG Haohui,et al. Research developments in cigarette smoke aerosol particle size distribution[J]. Acta Tabacaria Sinica,2014,20(2):108-113.
[9] Alderman S L,Ingebrethsen B J. Characterization of mainstream cigarette smoke particle size distributions from commercial cigarettes using a DMS500 fast particulate spectrometer and smoking cycle simulator[J]. Aerosol Science and Technology,2011,45(12):1409-1421.
[10] 段沅杏,赵伟,杨继,等. 传统卷烟和电子烟烟气气溶胶粒径分布研究[J]. 中国烟草学报,2015,21(1):1-5. DUAN Yuanxing,ZHAO Wei,YANG Ji,et al. Research on particle size distribution in traditional cigarette and electronic cigarette smoke aerosols[J]. Acta Tabacaria Sinica,2015,21(1):1-5.
[11] Wayne G F,Connolly G N,Henningfield J E,et al. Tobacco industry research and efforts to manipulate smoke particle size:Implications for product regulation[J]. Nicotine & Tobacco Research,2008,10(4):613-625.
[12] Health Canada. Determination of "tar, nicotine and carbon monoxide" in mainstream tobacco smoke[EB/OL]. (1999-12-15)[2017-12-01]. http://www.hc-sc.gc.ca/hc-ps/alt_formats/hecs-sesc/pdf/tobac-tabac/legislation/reg/indust/method/-main-principal/nicotine-eng.pdf.
[13] ISO 3308-2000 Routine analytical cigarette-smoking machine-Definitions and standard conditions[S].
[14] 张晓凤,戴亚,徐铭熙,等. 卷烟烟气气溶胶颗粒实时观测分析[J]. 中国烟草学报,2007,13(6):20-23. ZHANG Xiaofeng,DAI Ya,XU Mingxi,et al. Analysis and real time observation on cigarette smoke aerosol particles[J]. Acta Tabacaria Sinica,2007,13(6):20-23.
[15] Johnson T J,Olfert J S,Cabot R,et al. Steady-state measurement of the effective particle density of cigarette smoke[J]. Journal of Aerosol Science,2014,75:9-16.
[16] Ishizu Y,Ohta K,Okada T. Changes in the particle size and the concentration of cigarette smoke through the column of a cigarette[J]. Journal of Aerosol Science,1978,9(1):25-29.
[17] Hinds W C. Size characteristics of cigarette smoke[J]. American Industrial Hygiene Association Journal,1978,39(1):48-54.
[18] Baker R R,Dixon M. The retention of tobacco smoke constituents in the human respiratory tract[J]. Inhalation Toxicology,2006,18(4):255-294.
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