Abstract: To investigate the variations in the contents of chemical components in different strip sizes of cigarette blends and different lengths of cut fillers in finished cigarettes, principal component analyses were conducted on routine blend chemical components, polyphenols and non-volatile organic acids in strips of different sizes and cut fillers of different lengths. Systematic cluster analysis was carried out based on the scores of the first two principal components of three kind chemical indexes mentioned above, and the cluster analysis results of the chemical indexes of different length cut fillers were verified by a sensory panel evaluation. The results showed that:1) The distributions of principal component scores of the three kind chemical indexes of different size strips and different length cut fillers on two-dimensional plane presented distinctive variation trends. The strips of similar size and cut fillers of similar length fell into the same or adjacent regions. 2) With the decrease of strip size or cut filler length, the total content of routine chemical components was reduced linearly, the contents of polyphenols increased first and then decreased, the contents of non-volatile organic acids and the three kind chemical indexes presented a decrease trend of a logarithmic type. 3) According to the results of the cluster analysis based on the scores of the first two principal components, twenty samples of strips of five sizes were clustered into three categories (>21.97 mm, 4.32-21.97 mm, < 4.32 mm) and twenty-one samples of cut fillers of seven lengths were also clustered into three categories (>4.75 mm, 2.00-4.75 mm, < 2.00 mm). 4) The overall sensory quality of cut fillers of >4.75 mm significantly differed from that of cut fillers with < 4.00 mm length.