Abstract: In order to investigate the effects of material parameters, including air permeability of cigarette paper(APCP), air permeability of tipping paper(APTP), air permeability of plug wrapper(APPW), tow specifications(tow index I) of combined filter at mouth end(ITME) and tobacco end(ITTE), addition rates of filter additive A(benzoin resin, ARAA) and filter additiveB(bergamot oil, ARAB), on the benzoapyrene(BaP) delivery in mainstream cigarette smoke, the test cigarettes with various material combinations were prepared. The BaP delivery in mainstream cigarette smoke was analyzed against the said factors, and the optimized material combinations were verified. The results showed that: 1) APPW did not influence BaP delivery significantly, the other factors in the order of their effects on BaP delivery were ARAB > ITTE > ITME=APCP > APTP >ARAA, and interacted each other. 2) The optimized material combination for low BaP delivery were: APCP 50 CU, APTP 400 CU, ITTE 3.5 Y/34000, ITME 3.0 Y/35000, ARAA 2.436 mg/cig, and ARAB 2.100 mg/cig. 3) Comparing with monoacetate filter, the BaP delivery in mainstream smoke of cigarettes prepared with the optimized material combination decreased by 48.87%.