Abstract: In order to investigate the influences of temperature and relative humidity (RH) on the sensory indexes of cigarette, samples of a cigarette brand were evaluated in 16 cities, and their sensory indexes were analyzed by multilevel bicubic spline interpolation. The results showed that:1) In the temperature range of 4-10℃, flavor note, aroma quality, aroma quantity, harmony, strength, irritancy, cleanness and offensive odor scored lower. 2) In the temperature range of 10-20℃, flavor note, aroma quality, aroma quantity, strength, offensive odor, cleanness and irritancy scored higher at RH 30%-40%; harmony scored higher at RH 30%-70%. 3) At 20-30℃ and RH 30%-70%, harmony scored higher. 4) At 30-35℃ and RH 50%-70%, flavor note, aroma quality, harmony, strength and irritancy scored higher. 5) Taking into account the influences of temperature and relative humidity on the smoking sensation of cigarette and placing right products on major markets could ensure the better sensory quality of cigarette in the markets.