Abstract: To find out the relationships between filter ventilation rate and the deliveries of harmful components in mainstream cigarette smoke under different smoking regimes,the correlations between filter ventilation rate and the deliveries of nicotine and 13 harmful components(acetaldehyde,acrolein,benzene,benzoapyrene,1,3-butadiene,CO,formaldehyde,NNN,NNK,phenol,crotonaldehyde,HCN and NH₃) in mainstream cigarette smoke under ISO and Health Canada intensive(HCI) smoking regimes were investigated,and the correlations between filter ventilation rate and the deliveries of harmful components per unit nicotine yield were analyzed as well.The results showed that:1) Under ISO smoking regime,filter ventilation rate negatively correlated to the deliveries of harmful components(excluding NNN and NNK);filter ventilation rate negatively correlated to the deliveries of formaldehyde and crotonaldehyde per unit nicotine yield,while positively correlated to the deliveries of acetaldehyde,CO,benzoapyrene and NH₃ per unit nicotine yield.2) Under HCI smoking regime,filter ventilation rate negatively correlated to the deliveries of formaldehyde,crotonaldehyde,benzoapyrene,phenol and nicotine,while positively correlated to the delivery of HCN,there was no significant correlation between filter ventilation rate and the deliveries of the other harmful components.The deliveries of acetaldehyde,acrolein,crotonaldehyde,CO,HCN and NH₃ per unit nicotine yield also positively correlated to filter ventilation rate.