Abstract: In order to rapidly and accurately determine the benzoaanthracene, chrysene, benzoapyrene in mainstream cigarette smoke, an ionic liquid enrichment-GC/MS method was developed. The extraction, enrichment and stripping conditions were optimized, and 28 cigarette samples were analyzed by the developed method. The results showed that: 1) The optimal conditions were ultrasonic extracting for 40 min with methanol as the solvent, enriching for 2 min by adding 800 μL of ionic liquid C₆MIM PF₆ and 20 mL of water, then stripping for 5 min with cyclohexane. 2) The correlation coefficients of calibration curves ranged from 0.998 9 to 0.999 9. The limits of detection and quantification were 0.15-0.49 and 0.50-1.64 μg/L, respectively. The recoveries ranged from 81.24 % to 113.40 % with the relative standard deviation (RSD) no more than 5.0%. 3) There was no significant difference between the experimental results of this method and the results determined by the current industrial standard methods. This method was shown to be fast, accurate and suitable for analyzing the benzoaanthracene, chrysene, benzoapyrene in total particulate matter of mainstream cigarette smoke, and the consumption of organic solvents was significantly reduced.