Abstract: In order to detect the real-time temperature of e-cigarette liquids during vaporization, a detection method was established by adopting a temperature detection system consisted of superfine thermocouples. The effects of atomizer power, carrier liquid composition and vaporization duration on vaporization temperature were investigated. Synchronous thermal analysis by TG-DSC technology was used to analyze the effect of carrier liquid composition on vaporization temperature. The results showed that:1) The temperature detection system could detect in real time the temperature variation of a carrier liquid during vaporization process with a relative standard deviation (RSD) of 0.002%. 2) The heating rates of electric heating coil and wicking cotton were determined by the atomizer power, while the composition of the carrier liquid determined vaporization temperature at steady-state stage. The temperature of wicking cotton was lower than that of electric heating coil, vaporization process mainly occurred on the surface and vicinity of the coil. 3) Vaporization temperature was in the boiling point range of propylene glycol and glycerin. When glycerol concentration in the carrier liquid was less than 20%, the carrier liquid had a single boiling point, and vaporization temperature remained stable at steady-state stage. When the glycerol concentration was between 30% and 60%, the liquid had two boiling points, and vaporization temperature rose slowly at steady-state stage.