Abstract: To evaluate the effects of insecticides on Harmonia axyridis (Pallas), a filter paper contact method was adopted to detect the toxicity of seven recommended insecticides against H. axyridis in tobacco fields, and the effects of the seven insecticides on H. axyridis were evaluated by calculating their safety coefficients. The results showed that 2.5% cyhalothrin, 25 g/L deltamethrin and 4.5% beta cypermethrin had high toxicity to 3rd instar larvae of H. axyridis, and their LC₅₀ values to H. axyridis were 0.39, 0.43 and 5.89 mg/L, respectively. The LC₅₀ value of 70% imidacloprid was 128.36 mg/L. The toxicities of 3.2% abamectin, 25% thiamethoxam and 25% pymetrozine were lower to H. axyridis with the LC₅₀ value of 363.39, 391.22 and 1 074.20 mg/L, respectively. Considering the relative and absolute safety factors, 25 g/L deltamethrin to 3rd instar larvae of H. axyridis reached an extra high risk level, 2.5% cyhalothrin was between high and extra high risk levels, and 4.5% cypermethrin was between middle and high risk levels. The risk level of 70% imidacloprid was between low and high, and those of 3.2% abamectin, 25% thiamethoxam and 25% pymetrozine were low. Therefore, when the population of natural enemies was higher, thiamethoxam, abamectin and pymetrozine are preferentially recommended for controlling pests in tobacco fields.