Abstract: To alleviate the shortage of Brazilian tobacco in stock, the substitution of domestic tobacco for Brazilian tobacco was studied from two aspects, flavor style simulation and quality enhancement.By incorporating near infrared spectral projection and flavor style calibration, a flavor style distribution diagram of typical tobacco strip samples was established, and a domestic tobacco module with the major flavor style similar to that of Brazilian tobacco was screened out.The quality of the tobacco module was further enhanced by blending technique combined with chemical and sensory evaluation.The tobacco module was used as a substitute for Brazilian tobacco in cigarette production, the results showed that the near infrared spectra indicated that the style of Hubei tobacco was closest to that of Brazilian tobacco in general; the blended tobacco module(ZH-3)composed of middle and upper leaves of Hubei tobacco and upper leaves of Hunan tobacco could substitute as Brazilian tobacco; module ZH-3 was able to replace 5% of Brazilian tobacco in certain cigarette brands in Category Ⅰ or Ⅱ.