Abstract: In order to investigate the influences of chemical component variation in blended tobacco on cigarette blend maintenance, the chemical components in blended tobacco of 13 maintained blends of cigarette brand A manufactured by China Tobacco Guizhou Industrial Corporation in 2017 were analyzed by means of factor analysis, curve fitting, distance correlation analysis and cluster analysis. The results showed that:1) The comprehensive score curve of chemical component factors of each maintained blend could represent quantitatively the chemical components and sensory quality of the cigarette blend to facilitate the retrospective evaluation at the later stage of blend maintenance. 2) Through the distance correlation analysis of comprehensive score of chemical component factors, the extent of the difference between the chemical components in the maintained blends could be determined, and the fitness of each maintained blend could be judged intuitively and compared numerically. 3) In the long term of daily cigarette blend maintenance, the cluster analysis of factor comprehensive score could provide supports for maintaining the consistency and initial characters of chemical components in tobacco blends.