Abstract: In order to study style characteristics of cigarette brands, the chemical components in mainstream cigarette smoke of 25 leading cigarette brands were determined by gas chromatography/mass spectrometry. The yields of 335 chemical components in mainstream cigarette smoke were studied with independent sample t test and principal component analysis. The results of independent sample t test showed that the yields of 15 components in mainstream cigarette smoke of test group were significantly lower than control group samples. The yields of 17 components of test group were relatively higher than control group samples, where 6 components are known to have a sweetening effect. The results of principal component analysis indicated that most of test group samples were located in the same plane with shared commonness. Further study suggested that the shared commonness was closely related to moisture-retaining components in smoke. The above results provide technical support for study of style characteristics of cigarette brands.