Abstract: In order to assess the migration risk of heavy metals in metal assemblies of electronic cigarettes, a migration test method for identifying heavy metals was developed according to the actual conditions of metal assemblies' contacting with e-liquid, aerosol and mouth under storage and working conditions. The type and amount of simulant, the time and temperature of migration were determined. An ICP-MS (Inductively Coupled Plasma Mass Spectrometry) analysis method was developed for identifying nickel, chromium, lead, arsenic and cadmium as potential migrants in the following three simulants:a) aerosols; b) the mixture of propylene glycol, glycerol, nicotine and water; c) water. The migration amounts of heavy metals from metal assemblies in 30 e-cigarette samples were detected in the simulants. The sources of migration metals were also discussed. The results showed that:1) Nickel was migrated from heating coil to aerosols, and the migration amount was from 0.02 to 0.93μg per 200 puffs. 2) Lead was migrated from the metal assemblies contacting with e-liquid and aerosol, the migration amounts were 0.01 to 1.30 mg/kg, which mainly came from the impurities of copper-zinc alloy. 3) There was no migration risk of heavy metals from the metal assemblies contacted with mouth.