Abstract: In order to biologically control Anisopteromalus calandrae, a feasibility study on the reproductive capacity and control efficiency of A. calandrae to Lasioderma serricorne larvae was researched with indoor artificial inoculation at different wasp-pest ratios. The ability of A. calandrae to penetrate through different packaging materials was also analyzed. The results showed that: 1) When the ratio of A. calandrae to 5th instar larvae of L. serricorne was 2 pairs to 50 heads, the numbers of emergence female and adult wasps were the most, and the percentage of female adults reached the maximum. 2) The wasps could not penetrate packaging materials like kraft paper, carton, filter paper and plastic film, but could penetrate through existing holes with a diameter bigger than 0.18 mm. 3) The control efficiency of A. calandrae to 5th instar larvae of L. serricorne was more than 93.44% when the wasp-pest ratio was more than 4 pairs to 100 heads. Therefore, A. calandrae was a suitable natural enemy insect for controlling L. serricorne.