Abstract: Through analyzing the defects and causes of traditional techniques for order preference by similarity to ideal solution (TOPSIS) method, an improved TOPSIS method was established by using a combination of quadratic standardization, absolute ideal solution, analytic hierarchy process and new distance formula. The improved TOPSIS could fully reflect the superiority/inferiority of each evaluation object and was used to comprehensively evaluate the chemical quality of flue-cured tobacco from Sichuan Province. Furthermore, the evaluation results of the improved TOPSIS method were compared with those of traditional TOPSIS method and sensory quality evaluation method to verify the feasibility and rationality of the improved method. The results showed that: 1) Forty-five tobacco samples from Sichuan Province could be divided into three categories, and nearly 50% of the tobacco samples had medium or above chemical quality classifications. 2) Compared with traditional TOPSIS method, there was higher consistency between the evaluation results by the improved TOPSIS method and those of sensory quality evaluation method. Thus the improved method has improved reliability to comprehensively evaluate the chemical quality of flue-cured tobacco.