Abstract: In order to establish the relationships between the releases of chemical components in aerosol and heating temperature, central and peripheral electric heaters with different heating temperatures were prepared, and the ratios and releases of moisture, atomization agents, nicotine and aroma components in the aerosol at different heating temperatures were determined by gas chromatography(GC)and gas chromatography-tandem mass spectrometry (GC-MS-MS). The relationships between the releases of chemical components and heating temperatures were studied by hierarchical cluster analysis. The results showed that: 1)The releases of most chemical components increased with the rise of heating temperature under the two heating modes. 2)For the central heating mode, 300 ℃ and 380 ℃ were the key turning points. The chemical components in aerosol could be clustered into seven groups(R1 to R7)according to their release variations with the rising temperature, among them most compounds could be clustered in R1 and R2, accounting for 33.9% and 23.2% of the total number of compounds respectively. They could all be fitted into an exponential growth model, and their releases increased significantly when the temperatures were higher than 250 ℃ and 300 ℃ respectively. For the peripheral heating mode, 190 ℃ and 250 ℃ were the key turning points, and the chemical components in aerosol could be clustered into five groups(C1 to C5)according to their release variations with the rising temperature, among them most compounds were clustered in C1, C2 and C3, accounting for 26.1%, 21.7% and 23.9% of the total number of compounds, which were fitted into second-order polynomial, linear and exponential models respectively. The releases of compounds in Group C3 increased significantly at higher than 200 ℃. These results suggested that selecting suitable heating temperature was critical for optimizing aerosol taste and flavor of heated tobacco products based on the same tobacco material.