Abstract: To analyze the effects of heating temperatures on the TSNAs releases in aerosol of heated tobacco products, the release characteristics of TSNAs from three heated tobacco products at different heating temperatures were studied using an in-house designed heating device. The results showed that: 1) The TPM (total particulate matter) released from the three heated tobacco products increased with the increase of heating temperature, and it was extremely significantly linearly correlated with the heating temperature. 2) With the increase of heating temperature, the releases of NNN, NNK, NAB, and NAT and the total amount of TSNAs in the aerosol from the three heated tobacco products showed a significant quadratic increasing trend, increasing slowly at the lower temperatures and then significantly at the higher temperatures. 3) There were significant correlations between the releases of NNN, NNK, NAB, and NAT and the total amount of TSNAs with the different heating temperatures. 4) The releases of NNN, NAB, and NAT and the total amount of TSNAs in aerosol of heated tobacco products extremely significantly correlated with TPM release, which was different from traditional cigarettes.