Abstract: To promote the green and low-carbon transformation of cigarette factories, a multi-energy complementary heating system integrating solar collectors with multiple types of heat pumps was designed and constructed. A TRNSYS dynamic simulation platform was then established under typical operating conditions of the cigarette making and packing workshop at Hangzhou Cigarette Factory to simulate and evaluate the system. The simulation results indicate that, during the heating season, the system achieves an average COP of 4.2 and a waste heat recovery efficiency of approximately 81.2%. Economic analysis shows that the system has an annualized cost of 1.1204 million yuan, which is 27.9% lower than that of the traditional gas boiler system (1.5529 million yuan), demonstrating favorable economic performance and investment return potential. This study provides a theoretical basis and an engineering demonstration for the design and optimization of multi-energy collaborative heating systems in cigarette factories.