Abstract: By comparing different treatment processes for wastewater produced during tobacco processing, the technologies of reverse osmosis were specially designed on the basis of membrane bioreactor(MBR). It was found that external membrane module was preferable for tobacco wastewater treatment, and a system including water circulating, treating and reclaiming was established. The quality indexes of water, such as COD, turbidity, chroma, etc., primarily treated by MBR were up to the national standards. The water could be used in boiler and air-conditioner after further treatment. Taking Xuzhou Cigarette Factory as an example, wastewater treatment and reclamation could save 584 thousand RMB/year.