Abstract: The spatial variation of main nutrients in tobacco growing soil of Fangcheng County was analyzed with classical statistical and geostatistical methods.The results showed that:among 100 soil samples,the percentages of soil with low contents of organic matter(10 g/kg),alkali-hydrolyzable nitrogen(60 mg/kg),available phosphorus(10 mg/kg),available potassium(120 mg/kg)were 16%,55%,64%,71%,respectively,with moderate variance.The content of alkali-hydrolyzable nitrogen was strongly spatially autocorrelated,while organic matter(OM),available phosphorus and available potassium were moderately spatially autocorrelated;the interpolation map illustrated that OM content was low in the southeast part and south of the central part of Fangcheng,alkali-hydrolyzable nitrogen content low in northwest,north of the central parts and some of the southeast part,available phosphorus content low in the northwest and southeast parts,available potassium content low in the whole county except for some of the west and east parts.