Abstract: The application of SPC technology in the quality assurance of tobacco processing was studied.According to the requirements of redrying technology and the principle of SPC,a B/S-based quality SPC system was developed with C#,which incorporated production monitor network,fieldbus and quality management information system.The system unified the acquisition and storage of data with analysis and control of quality by means of Intranet and shared database to implement the automatic generation of the data of tobacco batch,record breakdown duration and fulfill statistical analysis,quality judgment and abnormal alarming for data of intra-and inter-batch or samples from packed tobacco with control graphs and histograms.The system configuration,OPC data acquisition,operational flow analysis,real time relational database,tobacco batch generation,program analysis flow,and development of object-oriented SPC graphical interface involving in the redrying system were analyzed.The practical application showed that the system was reliable and accurate,the abnormal fluctuation during flue-cured tobacco processing was reduced by monitoring and analyzing quality indexes in processing steps,the informatization and automation of quality SPC were realized,and the process control of threshing and redrying line was improved.