Abstract: Functionalized Mⁿ⁺ Amberlite IRC748 has been prepared by ion exchange for selectively reducing hydrogen cyanide (HCN) in cigarette smoke.By means of atom adsorption spectrometer (AAS),BET surface area analyzer and scanning electron microscopy (SEM),the exchange of metal ions,pore structure and surface morphology of Mⁿ⁺-IRC748 were characterized.The results showed that the transition metal ions in the order of adsorption amount by IRC748 were Cu²⁺ ≥ Zn²⁺> Co²⁺ ≥ Fe³⁺,which indicated that copper ion was more active to chelate with IRC748.The assessment by imitation filter device demonstrated that HCN in mainstream cigarette smoke could be reduced by Mⁿ⁺-IRC748 and up to 40% of HCN could be reduced by Cu²⁺-IRC748.The effects on reducing HCN from cigarette smoke were investigated by cigarette with a dual filter and the results indicated that 22.4% of HCN in cigarette smoke was reduced while the deliveries of nicotine and tar were almost unchanged,and there was no obvious sensory quality difference between experimental cigarette and the control cigarette.