Abstract: The effects of digestion solution volume and digestion temperature on the results of calcium and magnesium contents in cigarette paper determined by an autoanalyzer were investigated,and 20 cigarette paper samples were detected paralleled with ionic chromatography.The results showed that:1) The appropriated conditions for cigarette paper digestion were 0.2 to 0.3 g cigarette paper digested in 5 mL of perchloric acidnitric acid mixed solution at 300℃ for one hour.2) The recoveries of calcium and magnesium ranged from 96.7% to 102.9% and from 98.6% to 106.7% with the relative standard deviation (RSD) of 0.93% and 2.95%, respectively.3) The average contents of calcium and magnesium in domestic paper samples were 117.4 and 1.09,and in imported paper samples were 116.0 and 1.17 mg/g, respectively.4) There was no significant difference between the measurements of the two methods at 5% confidence level.It suggested that the method was suitable for the determination of calcium and magnesium in cigarette paper.