Abstract:
In order to evaluate the effects of cigarette and its plant additives on three symptoms,cough,ropy phlegm and asthma caused by smoking,the influences of the extracts from
Elettaria Maton,
Lauraceae and
Ericaceae composite,
Bignoniaceae and
Asteraceae composite,and smoke of the cigarettes containing the mentioned extracts on cough,tracheal excretion and tension of bronchial smooth muscle were evaluated by classic pharmacological evaluation models for respiratory system combining with functional properties of cigarette smoke. The results showed that by means of an in-house designed smoking device,it was feasible, applicable,and objective to evaluate the mentioned influences respectively by ammonia-induced cough test on mice,citric acid-induced cough test on guinea pig,phenol red excretion test,
in vitro trachea spiral strip test on guinea pig,and medicine-induced asthma test on integral animal.