Abstract: For identifying the cased cut tobacco in high-bay warehouse in the new Hangzhou Cigarette Factory, a Profibus-based RFID control system for the case filling station in primary processing line was designed, which was composed of master PLC, case filling PLC, RFID controller and RFID data acquisition terminal. Product information was written into the data label fixed on each cut tobacco case for subsequent tracing and tracking. The results of practical application showed that, the system ran reliably, the effective recognition rate reached 96.2%, which avoided the shortcomings of traditional paper barcodes and ensured the accuracy and security of the information about the cased tobacco. The data stored in RFID data label provided complete product information required by the process of receiving, retrieving, circulating and blending. The system implemented the functions of data inquiry, statistics analysis, derivation and printing and fulfilled the requirements of new production mode and batch management.