烟用水基胶中柠檬酸三丁酯和乙酰柠檬酸三丁酯的GC/MS测定

Determination of Tributyl Citrate and Acetyl Tributyl Citrate in Water-based Cigarette Adhesives with Gas Chromatography/Mass Spectrometry

摘要: 为测定烟用水基胶中的柠檬酸三丁酯(TBC)和乙酰柠檬酸三丁酯(ATBC),分别用正己烷、环己烷、乙醚、异辛烷进行了萃取烟用水基胶中TBC和ATBC试验,并采用气相色谱-质谱(GC/MS)/选择离子监测(SIM)法测定了烟用水基胶中的TBC和ATBC。结果表明:①以正己烷为萃取溶剂,0.3 g胶样中加入2 mL水,萃取体积10 mL,振荡30 min萃取效果较好。②方法线性关系良好,线性相关系数均大于0.99;TBC和ATBC的检出限分别为0.26和0.20μg/mL;回收率和RSD分别为96%~107%和3.93%~4.12%。该方法适用于烟用水基胶中TBC和ATBC的测定。

Abstract: In order to determine the tributyl citrate(TBC) and acetyl tributyl citrate(ATBC) in water-based cigarette adhesives,TBC and ATBC in the adhesive were extracted with n-hexane,cyclohexane,ethyl ether and 2,2,4-trimethylpentane,respectively,and then determined by GC/MS under selected ion monitoring mode.The results showed that:1) The optimal extraction conditions were 2 mL of water mixed with 10 mL of n-hexane(solvent) and 0.3 g of adhesive sample,and the mixture was oscillated for 30 minutes.2) The calibration curves of TBC and ATBC exhibited good linear relations(R²>0.99) with the limits of detection of 0.26 and 0.20 礸/mL,respectively.The recoveries ranged from 96% to 107% with the relative standard deviation(RSD) of 3.93% to 4.12%.This method is suitable for the analysis of TBC and ATBC in water-based cigarette adhesives.