Abstract: Two methods, HPLC and GC/MS, for determining benzoa pyrene (BaP) in cigarette smoke were developed.The pretreatment and instrument analysis condition were optimized and the repeatability, recovery and detectable limit of BaP were also determined.By comparing, a standard method was determined, wherein BaP in TPM was extracted with cyclohexane, then subjected to a silica SPE cartridge cleanup, and followed by quantitative analysis with GC/MS.For the method, the detectable limit of BaP was 1.44ng/mL, its recovery was in the range of 99.45%-102.40%, and CV was 2.77%.The BaP contents in 81 kinds of domestic and imported cigarettes were determined and the distribution of BaP yields of the cigarettes was discussed.