Abstract: The integral constitution of information network of Zhejiang tobacco industry was introduced, the safety requirements and goals of information network were analyzed, the constitution strategy of security system in the information network was proposed, also its implementation and the direction of development were introduced in detail. Technical measures applied in the network included fire wall, VLAN and VAN, antivirus, intrusion test, safety evaluation of loophole-scanning, analysis of network fault, backup and recovery. The basic functions such as protection, test, reaction and recovery were ensured, and the security of whole network was increased effectively.