Abstract: In order to study the practical control effect on tobacco brown spot and Myzus persicae (Sulzer),plot and indoor experiments on 5 mixtures of pesticide and bactericide, such as Admire+Carbcndazim+Dimethachlon, Decis+Dali, Meiyaning+Polyoxins, DDVP+Dimethachlon, Dipterex+Dimethachlon and Copper,were conducted with single agents as the contrast. The results showed that two mixtures, Admire at a dilution of 3000 + (Carbcndazim+Dimethachlon) at a dilution of 500 and Decis at a dilution of 2000+Dali at a dilution of 500, had better control effects both on tobacco brown spot and Myzus persicae (Sulzer).