Abstract: In order to determine suitable amounts of chlorine fertilizers in chlorine-deficiency areas, the field experiments on application of chlorine fertilizers were conducted. The potassium chloride was applied at 15, 30, 35, 60,75kg/ha, respectively. The treatments of 45 and 60 kg/ha showed the best results, the tobacco yield was the highest, the leaf had the best appearance and was rich in oil, the chlorine content of the leaf did not exceed the standard, and the ratio of potassium to chlorine was more harmonious. The treatments of 15 and 30 kg/ha were better. The residual chlorine in soil of 75 kg/ha treatment was close to the highest allowable value of tobacco field.