Abstract: The "Zhenxi" brand cigarette was made from natural abundant selenium tobacco.Its selenium contents were (3.0±0.5)μg/cigarette.In contrast with conventional cigarette, the harmful substances (free radicals, 3, 4-Benzopyrene, NOx, etc.)are significantly low in the smoke.So smoke "Zhenxi" brand cigarette can raise the smoker's blood selenium level, and improve smoker's immunolgical function.