Abstract: The resistance to insects of the transgenic tobacco cv 8611 expressing CPTI gene was tested.In comparitson with the control,mortality of the insects feeded on transgenic plants 8611.6 and 8611-11 reached 50% and 40% respectively,and the growth the:urvived insects were remarkeably inhibited.Under field condition,the in sects-damage index of progenies of 8611-6 and 8611-11 averaged 63.5% and 69.3/15 days after inoculation,averaged 37.7% and 39.8% 25 days after transplant,while that of the non-transformed control were 93.7% and 57%。these results demonstrated that it was possible to obtain insect protection in transgenic tobacco expressing CPTI gene.