Abstract: In order to effectively reduce the contents of chloride and nitrate in paper-making process reconstituted tobacco and improve the utilization efficiency of raw material, twelve kinds of anion exchange resins were tested to investigate the effects of temperature, processing duration, pH value, concentration, and the addition rate of anion exchange resin on the removal of chloride ions (Cl^-) and nitrate ions (NO₃^-) from tobacco stem extracts, and the reclaim and recycling of selected resins were studied. The results showed that: 1) Macroporous resin D202 was most effective in removal of Cl^-and NO₃^-. 2) When D202 was added into the tobacco stem extracts with the solid content of 8% at 40-45℃ for 5-7 minutes where the mass ratio of tobacco extracts to resin ranged from 0.8 to 1.0, the relative removal rates of Cl^-and NO₃^-reached more than 60% and 95%, respectively. Moreover, the application of treated tobacco extracts had no adverse effects on the sensory quality of reconstituted tobacco products. 3) After recycling for 10 times, the capacity of dechlorination and denitration of D202 basically unchanged.