Abstract: To investigate the effects of material parameters on the deliveries of seven harmful components in cigarette smoke, the deliveries of CO, HCN, NNK, NH₃, BaP, phenol and crotonaldehyde, in mainstream smoke of forty cigarette samples made with different cigarette paper, tipping paper and filters were tested according to single factor design. The results showed that:1) Phenol delivery decreased, while CO delivery increased with the increase of grammage of cigarette paper. 2) The deliveries of HCN, NH₃, BaP, CO and phenol significantly negatively correlated to the air permeability of cigarette paper, in the order of HCN>NH₃>BaP≈CO>Phenol. 3) The deliveries of NNK, NH₃, HCN, phenol, BaP and CO significantly negatively correlated to the pressure drop of filter rod, in the order of phenol>NH₃>NNK>HCN>BaP>CO. 4) The deliveries of the seven harmful components were affected by the air permeability of both tipping paper and plug wrapper to a certain extent,however the influence of air permeability of tipping paper was more obvious. Moreover, the influence of plug wrapper was enhanced by the increase of air permeability of tipping paper. 5) The deliveries of CO, NH₃, HCN, crotonaldehyde, phenol, and BaP significantly negatively correlated to the ventilation rate of filter, in the order of HCN>CO>crotonaldehyde>NH₃>Phenol>BaP.