Abstract: The traditional control system in primary processing line is not competent for the complicated and varied requirements of grouping processing because it is troublesome to restructure the technology, and the limitation of control module’s functions. Therefore, a control system based on the batch control technology in compliance with ISA88 standards was designed. The system was composed of equipment control level, centralized monitoring level and production management level. The model configuration was divided into four layers: process model, physical model, program control model and formulation model. The flexible and fine management and control for primary processing line were realized by means of the program design of BATCH control software, standardized program interface and system integration technology. The application results showed that the system met the requirements of grouping processing in terms of sectionalization, modularization, personalization and generalization, it shortened the time for system development, accelerated the speed of new product development, and improved production efficiency.