Abstract: The samples of cigarette attached with grooved filter plug were prepared, the plug wrapper was made of cellulose modified by polyethylene glycol/acetylpropionic acid/triethylene-glycol diacetate. The effects of the said cellulose modifiers on the deliveries of tar and phenol from cigarette smoke were studied. The results showed that: 1) In the case that the coating rate of modifiers was of (6.0±0.5)g/m², the modified cellulose wrapper had high efficiency for selective removal of phenol from cigarette smoke no matter whether its cellulose was modified by single modifier or their mixture. The sensory assessment of cigarette indicated that the taste and style of cigarette attached with grooved filter plug wrapper made of cellulose modified by acetylpropionic acid were pretty well preserved. 2) The removal efficency increased with the increase of modifier coating rate on the cellulose wrapper, furthermore, the high phenol removal efficiency would maintain for at least 2 months in the case that the coating rate of modifiers was of(9.0±0.5)g/m².3) In the case that the coating rate of acetylpropionic acid was of(9.0±0.5)g/m², the phenol removal rate was up to 33.31%, while tar delivery only reduced by 2.61%, the selective removal rate of phenol was 30.7%. In addition, in vitro toxicology tests of cigarette smoke indicated that acetylpropionic acid coating benefited to the reduction of health tisk of smoking.