摘要: In order to decrease harmful components in cigarette smoke, a tobacco blend was loosened and conditioned under a range of processing parameters with uniform design. Seven harmful smoke components in mainstream smoke of cigarette samples, including CO, HCN, NH₃, NNK, BaP, phenol, and crotonaldehyde, were determined. The results were treated with regression analysis and factorial analysis. The results showed that there was a significant linear relationship between the delivery of HCN and the parameters of loosening and conditioning, but not for other harmful components. The delivery of HCN was significantly affected by the combined effects of varying rotational speed of the drying cylinder, steam pressure, and recirculated air temperature. These results demonstrated that the loosening and conditioning parameters could be optimized to achieve lower HCN delivery in cigarette smoke.