Preparation of Nicotine Purity Reference Material

Reference material (RM) of nicotine purity was prepared. Six laboratories collaboratively confirmed quantitatively the purity of the prepared material by the method recommended by ISO 13276:1997"Tobacco and tobacco products-Determination of nicotine purity-Gravimetric method using tungstosilicic acid". The results showed that:1) The purity of RM of nicotine was 98.5% with the expanded uncertainty of 0.6%. 2) The prepared RM featured good homogeneity test result and higher stability during investigating period, and satisfied the technical requirements of national second grade reference material.